In historical context of Venice, proposing Institute of construction material research. This institute manage as a public and private institute. To make it public amenities such as exhibition, library and café area has been included in program. Fourteen principles of Biophilic design play as main key idea of design conceptualization. This Idea also help to reduce effect of pollution within the Building and increase productivity of occupants. Part of sustainable development locally sourced and carbon trap material such as Istrian stone, ferrock and timbercrete use as a building material.